Per- and polyfluoroalkyl substances (PFAS) and phthalates (two varieties of endocrine-disrupting chemical compounds) could also be related to decrease bone mineral density in male teenagers, in response to a brand new examine revealed within the Endocrine Society’s Journal of Medical Endocrinology and Metabolism.
Endocrine-disrupting chemical compounds are chemical compounds or mixtures of chemical compounds that intervene with the way in which the physique’s hormones work. Per- and polyfluoroalkyl substances (PFAS) are artificial chemical compounds utilized in nonstick cookware, clothes and meals packaging, and are more and more being present in US water provides. Phthalates are utilized in private care merchandise, meals processing and kids’s toys.
“Adolescence is a vital time when our our bodies construct up bone. Nearly all US kids and adolescents are uncovered to PFAS and phthalates, however few research have checked out how these chemical compounds could possibly be impacting our bone well being,” stated Abby F. Fleisch, MD , MPH, of the Maine Medical Heart Analysis Institute and Maine Medical Heart in Portland, Maine. “Our analysis discovered an affiliation between sure PFAS and phthalates and decreased bone mineral density in adolescent males. As a result of bone accrual primarily happens throughout adolescence, if replicated, this discovering could have implications for lifelong bone well being.”
The researchers leveraged urine and blood samples from 453 boys and 395 women from the Nationwide Well being and Diet Examination Survey (NHANES) and located greater ranges of PFAS and phthalates could also be related to decrease bone mineral density in adolescent males. The researchers didn’t discover the identical impact in women.
Different authors of this examine embody: Jenny L. Carwile, Shravanthi M. Seshasayee, and Clifford J. Rosen of the Maine Medical Heart Analysis Institute; Katherine A. Ahrens of the College of Southern Maine in Portland, Maine; Russ Hauser of the Harvard TH Chan Faculty of Public Well being in Boston, Mass.; Jeffrey B. Driban of the Tufts Medical Heart in Boston, Mass.; and Catherine M. Gordon of the Texas Kids’s Hospital and Baylor School of Drugs in Houston, Texas.
The examine obtained funding from the Nationwide Institute of Environmental Well being Sciences.